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Amlopres + Valzar 5/160 mg

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About the drug:

The combination drug Amlopres+Valsar consist of two ingredients. Amlodipine Besylate is a long acting Dihydropyridine-type calcium channel blocker. Valsartan is an Angiotensin II receptor antagonist and keeps blood vessels in a relaxed state.
Uses of the drug:

The combination of these both drugs is given in hypertension or high blood pressure. Lowering the high blood pressure (Hypertension) is helpful in preventing strokes, heart attacks and kidney problems. It is quite a helpful drug in increasing the ability to exercise and decrease the frequency of angina attacks.
Working of the drug:

Amlodipine Besylate is a calcium channel blocker. It works by inhibiting the movement of calcium ions through L type calcium channels into the vascular tissues and cardiac muscle cells. By inhibiting the entry of calcium channels, it decreases the contractility of arterial smooth muscles and causes vasodilation. This leads to relaxation of blood vessels and helps in the smooth blood flow, hence lowering the overall BP.
Valsartan is Angiotensin II receptor blocker to Angiotensin-I and is mainly found in tissues such as smooth muscles and adrenal glands. Angiotensin exerts vasoconstriction and aldosterone effects. This inhibition leads to dilatation of blood vessels and reduces blood pressure.

Amlopres +Valzar 5/160mg is manufactured by Cipla,India +torrent,India. The drug is available online to buy.

Dosage forms and strength:

Amlopres+Valzar 5/160 mg is available in the form of tablets. You can buy Amlopres+Valzar 5/160 mg online from alldaychemist.com at very cheap rates.
Before you take the drug:
• Do not take the drug if you:

     Are allergic to Amlodipine Besylate, Valsartan or any other ingredients
     Are pregnant or planning to become pregnant
     Are breastfeeding as the drug may pass into breast milk

• Tell your doctor if you:

     Are allergic to other ACE inhibitors
     Have liver problems
     Have unstable angina
     Have any other heart problems
     Have porphyria
     Have congestive heart failure
     Have heart disease or congestive heart failure etc.

How much to take the drug?

The drug should always be taken according to the prescribed by the physician. The general recommended dose starts from Amlodipine 10mg/ Valsartan 320 mg and can be increased or decreased depending upon the patient’s condition. Dose adjustments are generally done according to the progression of time and the response of the patient.
How to take the drug?

You must swallow the whole tablet with one glass full of water. Do not crush or chew it. Amlodipine Besylate is taken once daily with or without food. It is the best way to take medicine same time daily because it shows best results and helps to remember when to take the drug.
For how long to take it?

It is important to take the drug for the time period prescribed by the doctor. Sudden discontinuation of medicine or any kind of variation in the dose can cause adverse reactions. So, before stopping the drug intake, always consult your physician first.

You may need urgent medical attention if you experience below mentioned symptoms, due to accidental overdose of the drug:
• Dizziness
• Confusion
• Red skin rash
• Nausea
• Vomiting
• Diarrhea
• Fainting
• Rapid heart rate
Miss dose:

In case you miss the dose take it as soon as you remember. If it is almost time for your next dose, then skip the dose and take your next dose at the correct time. Do not double up the dose in order to compensate the missed one.
Side effects of the drug:

All medicines have their side effects, sometimes they are serious, but most of the times they are not. Common side effects are mentioned below:

• Nausea and vomiting
• Dizziness
• Tired feeling
• Stomach pain
• Flushing
• Swelling of legs or ankles

Serious side effects which need medical attention are as follows:

• Lightheadedness
• Fast heartbeat
• Chest pain
• Pain in arms or shoulders
• General illness
• Fatigue
Common drug interactions:

Always inform your doctor about the drugs you are taking till date. This way, the doctor is able to decide and give you the list of drugs and other things that may interact with Amlodipine Besylate. The following drugs are seriously contraindicated with Amlodipine:

• Dantrolene
• Simvastatin
• Diltiazem
• Ivacaftor
• Nefazodone
• Alfuzosin
• Calcium carbonate
• Calcium chloride
• Calcium citrate etc.
Things to remember:

• Keep a complete record of all the medicines you are taking along with this medicine
• Limit the intake of alcoholic beverages and avoid activity that requires alertness as it causes dizziness
• Monitor your blood pressure levels regularly
• In patients with coronary artery disease, angina and myocardial infarction may develop with this drug. So, there is a need to do dose adjustment
• Edema may develop in some patients within 2-3 weeks of starting the therapy

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