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IZRA 40 mg

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About the drug:

Esomeprazole is a proton pump inhibitor. This drug reduces the acid secretion in the stomach through inhibiting the hydrogen /potassium ATPase pumps in the parietal cells of the gastric walls.
Esomeprazole is the Enantiomer of Omeprazole. This drug is sold under various brand names across the world.

Uses of the drug:

Esomeprazole is used in the treatment of peptic ulcer disease, Gastroesophageal reflux disease (GERD/GORD), Zollinger–Ellison syndrome. But the drug is mainly prescribed for GERD and peptic ulcer.

Working of the drug:

Esomeprazole is a proton pump inhibitor. It prevents the moving back of food and acid into the esophagus as it prevents the overproduction of the gastric acid. It also gives relief from the symptoms along with the healing of the ulcers and wounds of the digestive pathway. This drug should be taken only when prescribed by the doctor /physician

Manufacturer:

The different manufacturers of the different strengths of Esomeprazole are:

Nexpro-20 mg-Torrent pharma
Nexpro-40 mg-Unichem India
Izra 40 mg- Unichem India
You can buy Esomeprazole online from our website alldaychemist.com at reasonable rates.

Dosage forms and strengths:

Esomeprazole tablets are present in two strengths under two different brand names on our website alldaychemist.com
• Nexpro-20 mg
• Nexpro-40 mg
• Izra -40 mg

Before you take the drug:

• Do not take if:

You are allergic to Esomeprazole or any other medicine containing proton pump inhibitors
You are younger than 1 years of age, as it is not prescribed for this age
You are pregnant and breast feeding, unless the doctor tells you to take the drug
You are taking Atazanavir or Cilostazol already as Esomeprazole hinders their action and vice versa

• Tell your doctor if:

You have a liver problem
You have a kidney problem

Dosage:

• How much to take the drug?

Take one tablet each day. Generally a dose of 20 mg or 40 mg a day is recommended. However, your doctor will decide the strength of the drug, according to the condition you are being treated and how severe it is.

• How to take?

Swallow Izra tablets whole with a glass full of water. Do not crush or chew it. If done so the tablet may not work effectively.
You must swallow the whole tablet with one glass full of water. It may be taken with or without food. Do not crush or chew it. If you find difficulty in swallowing the tablet follow these steps:

1. Take a half glass of non carbonated water(do not take mineral water or any other liquid drink)
2. Place the tablet in the water and stir it gently
3. Do not crush the tablet
4. Tiny pellets would be formed
5. Drink the pellets with water within 30 minutes, do not chew the pellets

If you cannot even drink, then the water along with pellets can be administered through a gastric tube.
Esomeprazole must be taken once a day. It is best to take it at the same time daily because it shows best results and helps to remember when to take the drug.

• For how long to take it?

Esomeprazole is a drug that relieves the symptoms completely and healing is usually complete within 4 weeks in most of the patients. Continue taking the drug as long as your doctor tells you.

You can buy Esomeprazole online from our website alldaychemist.com

• Overdose:

You may need urgent medical assistance. Even if you do not feel any signs symptoms of poisoning go to the nearest hospital or call the doctor immediately.

• Miss dose:

Take it as soon as possible if it’s not too late, but if it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to. Do not double up the dose to compensate for the missed one.

• Side effects of the drug:

Tell your doctor if you feel uncomfortable, you may need medical assistance if you undergo any of the following side effects:

• Nausea, wheezing
• Vomiting
• Constipation
• Stomach pain
• Rashes
• Dry mouth and dizziness
• Blurred vision
• Increased heart beat in males
• Tremors
• Hair loss

Some people may find severe side effects like:

• Pain or indigestion
• Blood /black stools
• Vomit blood or food, etc.
In these cases you may require immediate medical help. Do not get alarmed by the list. You may /may not experience all of them.

• Common drug interactions:

The following drugs should be avoided in case doctor prescribes you Esomeprazole in order to avoid possible drug interactions:

• Atazanavir and Nelfinavir
• Cilostazol
• Ketoconazole, Itraconazole and Voriconazole
• Diazepam
• St John's Wort - A herbal remedy used to treat mood disorders
• Warfarin
• Tacrolimus
• Digoxin

These medicines may be affected by Esomeprazole or may affect how well it works.

• Warning:

Things to remember:

• The drug must be taken in the same quantity as provided by the doctor
• Do tell your doctor if you are planning to use any new drug along with Esomeprazole
• Do not take the drug above its expiry date, and ask the pharmacist about the way of disposing of expired or left out drugs

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